Diabetes protected from the retina to destroy activated receptors

Diabetes can do to beautify the retina floor above - like fried bacon.

It is known as a drug - easing the pain of power and memory to stimulate the retina damage is believed to prevent blindness appears that connection, the researchers say.

"This drug awe-inspiring impact on the health of the retina," says Dr. Sylvia Smith, retinal cell biologist and co - the Discovery Institute's Director of the Medical College of Georgia medical school vision. She is comparing the images of the retina, rat model for diabetes treatment () - pentazocine was not idle. Even that did not receive any snow, the difference is dramatic.

Research, publications, video, inside and scientific investigation in September issue, suggested that compounds such as sigma receptors in the eyes of the combination therapy a good suit top two causes of blindness 2006: diabetic retinopathy, glaucoma.


Sigma receptors in the body is ubiquitous, but their roles and what they are, of course, unknown active. Recent studies imply an appropriate level of protection sigma receptor cells to stress appropriately secured gaeeo the normal function of proteins is required. Dr. Smith said it appeared Sigma, and other locations within the endoplasmic reticulum to the cell receptor protein synthesis and controls to adjust the level of calcium. When necessary, they will appear in cell receptor protein guardian powerhouse, or mitochondria. Dr. Smith suspects hotbed of Sigma's cell receptors to help manage the stress. In fact, sigma receptors and the cells are bound to increase stress pentazocine.

Give the role of protecting the retinal cells to help get the urge bit nervous hands, the transformation is happening in the brain. Regularly insulted in the same light. Retina tolerate suit or high blood sugar, and continue to work in a few years. For example, in the case of diabetic retinopathy, the progressive nerve cell death and damage blood vessels and eventually a new attempt to encourage more blood and oxygen to the cells to die, obviously. Instead, the result is more blood vessels proliferate blindness.

Dr. Smith Institute of peace without the cooperation of the mouse and other breeds mcg sigma receptors receptors in the role of investigators to effectively understand and medication regularly, and whether they affect other animals of similar model for retinal disease dramatically. "We need to know that we're just lucky jackpot Akita mouse or something that we benefit from a comprehensive hands."

Interestingly, the sigma receptors affect the level of insulin can not bind the pentazocine. "This is a diabetic does not solve the problem; However, our survey results suggest that there is reason gohyeoldang does not mean that diabetic retinopathy," Dr. Smith says.

Sigma Research Institute to accept her the potential to prevent diabetes' is pioneering the establishment of a waterfall, but accept Sigma is a hot topic. Scientists are exploring their potential to treat the problem as depression, Alzheimer's brain tumor. The early as September, there was also a 2700 paper's literary sigma receptors, says Dr. Smith.

Source : Medical College of Georgia