Johns Hopkins researchers suppressing 'hunger hormone'

Johns Hopkins scientists report significant levels of success in suppressing the "hunger hormone" ghrelin pigs by using a minimal invasion of Sudan's main vessel carrying blood to the gasification of the top section of the chemical, or floor, above. About 90 percent of ghrelin in the body of hormones that occur on the show floor you can not do without a good blood supply.

"Chemicals called up artery embolization gace, nothing major surgery," he says aravind arepally MD, clinical director of the Center for biotechnology innovation and design and an assistant professor of radiology and surgery at John Hopkins University medical school. "Our research on pigs, production procedures to affect ghrelin levels similar to perform obesity surgery cuts the appetite suppressants in a row."

September 16 report on the research work in the online version of Radiology, arepally assistance and his team is more than 10 years, efforts to suppress safely and easily met with very limited success of grehlin.

Obesity surgery - removal of the relationship, reconstruction or stomach or bypass part of a boss - effectively suppresses appetite and leading to significant weight loss, but the actual surgery carries risks and complications. "The biggest problem of obesity in this country is also a big difference in medicine and minimally invasive replacement boilsu performance and options for obese people," arepally says.

Their research fellow arepally This process is less than four weeks and 10 using a healthy, growing pigs; after overnight fast, and all the animals are weighed and blood samples were taken by measuring the levels of ghrelin. The pig is the best choice, he says, the human - because, like the anatomy and physiology.

Used x - Guidelines for Ray, a member of the team is thin tube through a blood vessel near the screws a big pig 'groins cover up the artery supplying blood. Here, one of them injected with saline injections - five hours of top-left of the control pig arteries, and the other five, 1 - injections of sodium morrhuate time off, destroying the blood vessels caused by chemical substances.

The following sample pig teams' monitors the value of ghrelin in the blood for one month. The levels of hormones gace - a pig with a maximum of 60 percent or more of treatment by others.

"Appetite is complicated because it includes both physical and mental," arepally says. "ghrelin fluctuates throughout the day, all kinds of emotions and physiological responses to the scenario. noeuineun, even" more productive ghrelin, "is creating a hunger hormone gace physically prevent it from the top."

Source : Johns Hopkins Medical Institutions